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Lecturer(s)
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Fuksová Markéta, Mgr.
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Bieleszová Kristýna, Mgr.
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Klos Dardan, Mgr.
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Doležal Karel, Mgr. Dr.
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Žukauskaite Asta, Dr., Ph.D.
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Hönig Martin, Mgr.
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Plíhalová Lucie, Mgr. Ph.D.
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Bryksová Magdaléna, Mgr. Ph.D.
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Chrenko Daniel, Mgr.
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Kubaláková Beáta, Mgr.
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Pospíšil Tomáš, Mgr. Ph.D.
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Course content
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Biogenous elements, carbon, binding capacity of carbon, bond types, stereochemistry of molecules, isomerism. Nomenclature of organic compounds. Reaction mechanisms. Inductive and mesomeric effects. Homolysis and heterolysis. Substitution, elimination, addition and rearrangement reactions. Oxidation and reduction of organic compounds. Carbohydrates: alkanes, alkenes, alkynes, aromatic compounds. Hydroxoderivatives: alcohols and phenols. Ethers. Amines. Nitrocompounds. Carbonyl compounds: aldehydes and ketones. Carboxylic acids and their functional (halogenides, anhydrides, amides, esters) and substitutional (hydroxyacids, oxoacids) derivatives. Carbonic acid derivatives. Heterocyclic compounds. 5-, 6-membered rings with O, S, N. Purine and pyrimidine derivatives, DNA, RNA. Alkaloids. Aminoacids. Peptidic bond and their properties. Peptides and proteins, enzymes. Vitamins. Saccharides: mono-, oligo- and polysaccharides. Reactions of saccharides. Derivatives of saccharides, glycosides. Lipids: simple and compound lipids. Photosynthesis (primary and secondary processes). Catabolic processes. Oxidation. Glycolysis and following aerobic and anaerobic processes. Terpenes and steroids.
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Learning activities and teaching methods
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Lecture
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Learning outcomes
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The object of the lectures is to learn basics of organic chemistry relationship in biological systems. It constists of following chaptures: Biogenous elements, carbon, binding capacity of carbon, bond types, stereochemistry of molecules, isomerism. Nomenclature of organic compounds. Reaction mechanisms. Inductive and mesomeric effects.Steric effects. Homolysis and heterolysis. Substitution, elimination, addition and rearrangement reactions. Oxidation and reduction of organic compounds. Carbohydrates: alkanes, alkenes, alkynes, aromatic compounds. Hydroxoderivatives: alcohols and phenols. Ethers. Amines. Nitrocompounds. Carbonyl compounds: aldehydes and ketones. Carboxylic acids and their functional (halogenides, anhydrides, amides, esters) and substitutional (hydroxyacids, aminoacids, oxoacids) derivatives. Carbonic acid derivatives. Heterocyclic compounds. 5-, 6-membered rings with O, S, N. Purine and pyrimidine derivatives, DNA, RNA. Alkaloids. Aminoacids. Peptidic bond and their properties. Peptides and proteins, enzymes. Vitamins. Saccharides: mono-, oligo- and polysaccharides. Reactions of saccharides. Derivatives of saccharides, glycosides. Lipids: simple and compound lipids. Biomolecules and their chemical principles.
Describe and explain: Biogenous elements, carbon, binding capacity of carbon, bond types, stereochemistry of molecules, isomerism. Nomenclature of organic compounds. Reaction mechanisms. Inductive and mesomeric effects. Homolysis and heterolysis. Substitution, elimination, addition and rearrangement reactions. Oxidation and reduction of organic compounds. Carbohydrates: alkanes, alkenes, alkynes, aromatic compounds. Hydroxoderivatives: alcohols and phenols. Ethers. Amines. Nitrocompounds. Carbonyl compounds: aldehydes and ketones. Carboxylic acids and their functional (halogenides, anhydrides, amides, esters) and substitutional (hydroxyacids, oxoacids) derivatives. Carbonic acid derivatives. Heterocyclic compounds. 5-, 6-membered rings with O, S, N. Purine and pyrimidine derivatives, DNA, RNA. Alkaloids. Aminoacids. Peptidic bond and their properties. Peptides and proteins, enzymes. Vitamins. Saccharides: mono-, oligo- and polysaccharides. Reactions of saccharides. Derivatives of saccharides, glycosides. Lipids: simple and compound lipids. Photosynthesis (primary and secondary processes). Catabolic processes. Oxidation. Glycolysis and following aerobic and anaerobic processes. Terpenes and steroids.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Mark
80% fruitfulness in exam
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Recommended literature
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Červinka O., Dědek V., Ferles M. (1980). Organická chemie. SNTL Praha.
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Lucie Szüčov. (2011). Chemie pro biology II.. Univerzita Palackého v Olomouci, Olomouc 2011.
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N.A. Campbell, b. williamson, R.j. Heyden:. (2006). Biology: Exploring Life.. Boston, Massachusetts, Pearson Prentice Hall, 2006.
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Raymond, K.W. (2006). General, Organic and Biological Chemistry: an integrated approach. John Wiley & Sons, New York.
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Solomons G., Fryhle C. (1999). Organic Chemistry 7th. John Wiley & Sons, New York.
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