| Course title | Organic Chemistry 2 |
|---|---|
| Course code | OCH/OC2 |
| Organizational form of instruction | Lecture + Seminar |
| Level of course | Bachelor |
| Year of study | not specified |
| Semester | Winter |
| Number of ECTS credits | 3 |
| Language of instruction | Czech |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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1. Introduction, summary of OC1 (Alkanes, alkenes, alkynes, electrophilic substitution, aromates, mesomeric effects, electrophilic aromatic substitution, halogen derivatives, nucleophilic substitution and elimination). 2. Hydroxy derivatives - alcohols and phenols. 3. Ethers - physical properties in comparison with alcohols.Thioles and sulfides. Comparison with the oxygen derivatives. Products of oxidation - sulfinic and sulfonic acids, sulfoxides and sulfones. Sulfonic acids and their derivatives, their preparation and reactivity, application. 4. Amino derivatives - the basic chemical properties. Hofmann rearrangement. Reactivity of amines with nitrous acid. Diazotization and diazonium salts, coupling reactions. Quaternary amonium salts. Hofmann elimination. Reactions with phase transfer catalysis. Diazocompounds. Diazoalkanes, diazoesters, diazoketones. Arndt-Eistert-Wolf rearrangement. Azides. Nitro compounds. Structure and reactivity. Influence of the nitro group on the carbon skeleton. Preparation of nitro compounds. Ambident ions. Reduction of nitro compounds. Azo, azoxy and hydrazo compounds. Nitriles and isonitriles. Structure and reactivity and preparation. Hydrolysis of nitriles. 5. Carbonyl derivatives 1. 6. Carbonyl derivatives 2. 7. Carboxylic acids, their structure, representatives, chemical properties. Influence of the carbon rest on the acidity. Esterification. 8. Function derivatives of carboxylic acids (halogen derivatives, anhydrides, esters, amides, nitriles, hydroxamic acids, hydrazides, azides). Preparation and comparison of their properties. 9. Substitutional derivatives of carboxylic acids (halogen derivatives, hydroxy derivatives, amino acids, keto acids). 10. Carbohydrates (aldoses, ketoses, trioses, tetroses, pentoses, hexoses), nomenclature. Mutarotation and cyclic form. 11. Heterocyclic compounds (five- and six-membered heterocycles).
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| Learning activities and teaching methods |
| Lecture |
| Learning outcomes |
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Specialized course focusing on the study of properties and reactivity of organic compounds and their synthesis.
Define main concepts, describe main approaches, learn basic chemical reactions, present system of the organic chemistry. |
| Prerequisites |
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Folllowing course OC1, the course OC2 extends the properties and reactions of other derivatives.
OCH/OC1 |
| Assessment methods and criteria |
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Written exam
Credit will be given in case of passing written test during the semester at least 60%. For the exam the student is allowed only when successfully gets the credit. The exam is written (at least 60%). |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biochemistry (2022) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Bioinorganic Chemistry (2021) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Bioorganic Chemistry and Chemical Biology (2020) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Chemistry for Education (2024) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Chemistry - Analytical Specialist (2021) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Chemistry (2019) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Nanomaterial Chemistry (2024) | Category: Chemistry courses | 2 | Recommended year of study:2, Recommended semester: Winter |