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Lecturer(s)
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Kristek Jozef, Mgr.
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Profous David, Mgr.
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Hrabalová Michaela, Mgr.
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Dak Milan, RNDr.
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Lemrová Barbora, Mgr. Ph.D.
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Žáková Kateřina, Mgr.
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Pokorný Jan, Mgr. Ph.D.
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Bachořík Jan, Mgr.
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Sokol Radoslav, Mgr.
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Chasák Jan, Mgr.
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Kolařík Michal, Mgr.
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Cankařová Naděžda, RNDr. Ph.D.
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Kováč Ondřej, Mgr. Ph.D.
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Vychodilová Kristýna, Ing. Ph.D.
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Orság Šimon, Mgr.
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Course content
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Introduction to organic chemistry - definition of organic chemistry. Carbon and its position in the periodic table and properties resulting therefrom - binding ratios, hybridization, atomic and molecular orbitals, binding angles. Bind \{pi} and \ {delta}. Hydrogen bonds. Partial charge determination. Drawing Lewis formulas. Drawing organic formulas. 2. Nomenclature. Fundamentals of stereochemistry (isomerism, conformation, configuration, chirality). Drawing formulas using Newman projection, Fisher projection, spatial formulas. Redraw cyclohexane into both chairs ("e" and "a" bindings). 3. Drawing of chemical structures - simplified entries, functional groups, drawing of mechanical arrows. Nucleophilicity and electrophilicity. Oxidation degrees of carbon in organic compounds / formal charge, hierarchy of functional groups. 4. Induction and mesomeric effect. Conjugation. Drawing of mesomeric formulas. 5. Acids and bases - Bronsted definition, acid and base strength, pH and pKa, and its use to predict acid-base reactions. Organic acids and organic bases, Lewis definition. Nucleophility x basicity. C-acids. 6. Overview of mechanisms of organic reactions - additions (nucleophilic, electrophilic, radical), substitution (nucleophilic, electrophilic, radical), elimination, rearrangement, pericyclic reactions. 7. Alkanes - properties and reactivity. 8. Alkenes - properties and reactivity (often stereochemical effects) 9. Alkynes - properties and reactivity. 10. Aromatic compounds - properties and reactivity. 11. Organometallic compounds. 12. Pericyclic reactions
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Learning activities and teaching methods
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Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming)
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Learning outcomes
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The seminar is focused on explaining and practicing problems associated with the synthesis of organic derivatives.
To analyze information, to solve model problems, to explain the chemical properties of derivatives of organic molecules and their transformation.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam, Seminar Work
Regular attendance at the seminar. Passing a written test - obtain at least 60% points.
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Recommended literature
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Clayden J, Greeves N. Warren S. (2012). Organic chemistry.
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Červinka O., Dědek V., Ferles M. (1980). Organická chemie. SNTL Praha.
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McMurry J. (2015). Organická chemie. VŠCHT Praha.
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McMurry, S. Studijní příručka a řešené příklady k 6. vydání učebnice J. McMurry: Organická chemie.
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