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Lecturer(s)
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Sokol Radoslav, Mgr.
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Kristek Jozef, Mgr.
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Profous David, Mgr.
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Vychodilová Kristýna, Ing. Ph.D.
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Jedináková Petra, Mgr. Ph.D.
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Lemrová Barbora, Mgr. Ph.D.
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Cankařová Naděžda, RNDr. Ph.D.
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Kováč Ondřej, Mgr. Ph.D.
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Bachořík Jan, Mgr.
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Dak Milan, RNDr.
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Chasák Jan, Mgr.
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Course content
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1. Summary of OC1. 2. Hydroxy derivatives - alcohols and phenols. 3. Ethers - physical properties in comparison with alcohols.Thioles and sulfides. Comparison with the oxygen derivatives. Products of oxidation - sulfinic and sulfonic acids, sulfoxides and sulfones. Sulfonic acids and their derivatives, their preparation and reactivity, application. 4. Amino derivatives - the basic chemical properties. Hofmann rearrangement. Reactivity of amines with nitrous acid. Diazotization and diazonium salts, coupling reactions. Quaternary amonium salts. Hofmann elimination. Reactions with phase transfer catalysis. Diazocompounds. Diazoalkanes, diazoesters, diazoketones. Arndt-Eistert-Wolf rearrangement. Azides. Nitro compounds. Structure and reactivity. Influence of the nitro group on the carbon skeleton. Preparation of nitro compounds. Ambident ions. Reduction of nitro compounds. Azo, azoxy and hydrazo compounds. Nitriles and isonitriles. Structure and reactivity and preparation. Hydrolysis of nitriles. 5. Carbonyl derivatives 1. 6. Carbonyl derivatives 2. 7. Carboxylic acids, their structure, representatives, chemical properties. Influence of the carbon rest on the acidity. Esterification. 8. Function derivatives of carboxylic acids (halogen derivatives, anhydrides, esters, amides, nitriles, hydroxamic acids, hydrazides, azides). Preparation and comparison of their properties. 9. Substitutional derivatives of carboxylic acids (halogen derivatives, hydroxy derivatives, amino acids, keto acids). 10. Carbohydrates (aldoses, ketoses, trioses, tetroses, pentoses, hexoses), nomenclature. Mutarotation and cyclic form. 11. Heterocyclic compounds (five- and six-membered heterocycles).
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Learning activities and teaching methods
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Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming)
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Learning outcomes
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At Seminar there are explained and exercised chemical properties of derivatives of organic molecules and their chemical transformations on examples. It helps to understand the theoretical knowledge achieved during Organic Chemistry 2 course.
Analyze information, outline the solution of model problems, explain chemical properties of derivatives of organic molecules and their chemical transformations. Student will be familiar with basic chemical reactions within the organic chemistry.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam
Regular attendance of seminar. Successful passing of written examination - obtaining of at least 60% of credit points.
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Recommended literature
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Červinka a kol. (1985). Organická chemie. Praha.
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McMurry, J. Organická chemie.
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McMurry, S. Studijní příručka a řešené příklady k 6. vydání učebnice J. McMurry: Organická chemie.
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Potáček, M. et al. (2009). Řešené příklady z organické chemie. Brno.
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Slouka J., Wiedermannova I. (2003). Průvodce některými úvodními kapitolami organické chemie. UP Olomouc.
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