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Lecturer(s)
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Brisudová Aneta, Mgr.
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Fritzová Dominika, MUDr.
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Szczyrbová Eva, Mgr.
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Urbánková Markéta, Mgr. MUDr. Ph.D.
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Šimková Dana, Mgr. Ph.D.
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Gachechiladze Mariam, Ph.D.
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Ehrmann Jiří, prof. MUDr. Ph.D.
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Bouchal Jan, doc. Mgr. Ph.D.
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Überall Ivo, Ing. Ph.D.
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Weiser Drozdková Denisa, Mgr.
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Voller Jiří, Mgr. Ph.D.
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Course content
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The aim of the course is to introduce the students to the essentials of molecular pathology, with emphasis on practical usage in predictive pathology and prognosis of tumour. The subject is also concerned with study of cell cycle, apoptosis and its disregulation, oncogenes and tumour supressor genes, as well as gene therapy.
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Learning activities and teaching methods
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Monologic Lecture(Interpretation, Training), Projection (static, dynamic)
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Learning outcomes
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Molecular pathology (MP) is the study of the etiology and pathogenesis of disease through the analysis of molecular modifications of cells and tissues, and as a profession it involves using the knowledge of the etiopathogenesis of the disease to make a diagnosis and give prognostical and therapeutical information.
The student will be able to implement knowledge of molecular pathology into consequent scientific activity and into diagnostic-therapeutic process.
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Prerequisites
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Knowledges from biology and physiology.
PAT/VCA11
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Assessment methods and criteria
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Didactic Test
90 % attendance at classes. Successfull passing the test = minimal 75% of correct answers is required.
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Recommended literature
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Alberts B. et al. Molecular Biology of the Cell. Garland Science 2014 (or Essential Cell Biology, Garland Science 2013)..
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Cagle PT and Craig T. Basic concepts of molecular pathology. Springer 2009..
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Hanahan et Weinberg. (2011). Hallmarks of Cancer: The Next Generation..
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Müllauer L. Milestones in pathology-from histology to molecular biology. Memo 2017; 10: 42-45..
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Tubbs RT and Stoler MH. Cell and tissue based molecular pathology. Churchil Livingstone, 2009.
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