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Lecturer(s)
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Popper Miroslav, MVDr. Ph.D.
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Džubák Petr, MUDr. Ph.D.
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Hajdúch Marián, doc. MUDr. Ph.D.
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Petřík Miloš, doc. PharmDr. Ph.D.
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Course content
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History of animal research. The ethics of animal research. Animal research legislation. Animal facilities, classification and characteristics (conventional, breeding, GMO, SPF), specialised equipment. Animal welfare (laboratory and experimental conditions). Review of laboratory animals, descriptions of the species and strains, their specifics, advantages and disadvantages. Principles of experimental work (handling, labelling, testing, sampling of biological material, drug administration, microsurgery, anaesthesia, euthanasia). Experimental animal models (cancer, metabolic, neurodegenerative, infectious diseases). Case studies of animal models based on selected publications. Visit of the IMTM animal and core imaging facility (X-ray, PET/SPECT/CT, fluorescence, luminescence, ultrasound.
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Learning activities and teaching methods
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Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Projection (static, dynamic)
- Attendace
- 0.5 hours per semester
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Learning outcomes
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The aim of the subject is to provide students with a general overview of the methods of care and experimental work with laboratory animals and their use as study models of human diseases.
Students will gain knowledges about experimental work with laboratory animals and their use in the study of human diseases.
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Prerequisites
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Finished the third year of the study.
BIO/VCB11
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Assessment methods and criteria
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Student performance, Dialog, Systematic Observation of Student
Knowledge in the range of course matter and recommended literature and knowledge of animal welfare and basic principles of the animal handling.
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Recommended literature
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Doležal, D., Večerka, J. (2011). Práce s laboratorními zvířaty. Laboratorní myš, potkan a králík. Univerzita Palackého v Olomouci, 1. vyd.
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