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Lecturer(s)
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Kolář Milan, prof. MUDr. Ph.D.
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Hamal Petr, doc. MUDr. Ph.D.
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Sauer Pavel, Mgr. Ph.D.
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Imwensi Peter, MUDr.
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Raclavský Vladislav, doc. MUDr. Ph.D.
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Mlynárčik Patrik, Mgr. Ph.D.
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Course content
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Characterization of procaryotic cells. Inner structures in bacteria. Surface structures in bacteria. Spores. Growth and reproduction of bacteria. Bacterial pathogenicity and virulence. Exotoxins and endotoxins. Microbial ecology. Microorganisms in healthy human body. Bacterial metabolism and enzymes. Bacterial genetics. Mutation. Gene transfer. Lysogenic conversion. Plasmids. Transposons. Easter Monday. Resistance of microbes to antibiotics (mechanisms and spreading). Antimicrobial agents - classification. Appropriate antibiotic therapy. Sterilization and disinfection. Antigens. Active immunization. Antibodies. Passive immunization. Endogenic infections. Nosocomial infections.
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Learning activities and teaching methods
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Lecture, Observation, Demonstration, Projection (static, dynamic), Laboratory Work
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Learning outcomes
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To practice basic skills and measures in working with infectious materials. To acquire knowledge of taxonomy, morphology, genetics and physiological properties of microroganisms. To gain an overview of diagnostic methods and microbiology laboratory services. To be capable of selecting the most suitable examinations. To become familiar with antimicrobial agents, their prophylactic and therapeutic use, and with the principles of disinfection and sterilization.
The students will be able to implement the acquired knowledge and skills both in the diagnostic and therapeutic approach to patients and in scientific and research activities.
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Prerequisites
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Successful completion of biology, anatomy, latin and medical chemistry.
BIO/VAB11 and LCH/VAA11 and LBF/VAB11 and CJA/VAB41 and CJA/VA031 and NAN/VAB13 and NAN/VAA13 and PVL/VAB71 and LCH/VAB20 and HIE/VAB11 and KAR/VAB11
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Assessment methods and criteria
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Student performance
Presence in all practical trainings
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Recommended literature
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Goering, R. et al. (2016). Mimsova lékařská mikrobiologie. Praha: Stanislav Juhaňák - Triton.
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Koukalová, D. a kol. (2013). Microbiology I. Olomouc: Univerzita Palackého v Olomouci.
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Murray, P.R., Rosenthal, K.S., Pfaller, M.A. (2012). Medical Microbiology. Saunders.
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