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Lecturer(s)
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Ulrichová Jitka, prof. RNDr. CSc.
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Anzenbacherová Eva, doc. RNDr. CSc.
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Course content
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Basic building units of living systems. Water and ion management disorders. Structure and function of proteins. Enzymes and their use in the diagnosis of diseases. Biological oxidation. Respiratory chain, aerobic phosphorylation. The citric acid cycle. Metabolism of carbohydrates and lipids - metabolic disorders and their diagnosis. Overview of metabolic pathways of amino acids. Urea cycle. Regulation of basic metabolic processes. Low molecular mediators and their functions. Hormones, vitamins. Metabolism of xenobiotics. Cell models in biochemistry and toxicology, detoxification function of liver.
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Learning activities and teaching methods
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Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook), Laboratory Work
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Learning outcomes
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The aim of the course is to explain the principles of biochemical processes in the organism at the molecular level and at the same time to explain mechanisms of regulation of basic metabolic processes. This knowledge is a prerequisite for the interpretation of physiological and pathological processes in the human organism.
Students will acquire an overview about basic metabolic processes occurring in the body, including regulations. From practical aspect, students will be able to carry out simple biochemical analyses including interpretation of results.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam, Dialog
Active participation in seminars.
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Recommended literature
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Dobrota, D. (2012). Lekárska biochémia. Martin: Osveta.
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Dvořáčková, S. (2013). Pracovní sešit z biochemie. Olomouc.
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Ledvina, M. a kol. (2009). Biochemie pro studující medicíny (1. a 2. díl). Praha - Karolinum, UK.
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Matouš, B. (2010). Základy lékařské chemie a biochemie.
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