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Lecturer(s)
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Anzenbacherová Eva, doc. RNDr. CSc.
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Jourová Lenka, Mgr. Ph.D.
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Course content
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Topics of lecturers and practical lectures: 1.Basic building units of living systems. 2.Structure and function of proteins. Enzymes and their use in the diagnosis of diseases. 3.Biological oxidation. Oxidoreduction chain, aerobic phosphorylation. 4.Citrate cycle. 5.Metabolic pathways of carbohydrates and lipids - metabolic disorders and their diagnosis. 6.Overview of metabolic amino acid transformations. Ureosynthetic Cycle. 7.Regulation of basic metabolic processes. Low molecular mediators and their functions. Hormones, vitamins. 8.Metabolism of xenobiotics. Cell models in biochemistry and toxicology, liver detoxification function.
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Learning activities and teaching methods
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unspecified
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Learning outcomes
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The course is aimed to explain the theoretical principles of mechanisms and regulation of basic metabolic processes. This knowledge is a prerequisite for the interpretation of physiology and pathological processes in the human organism.
The aim of the subject is to explain the theoretical principles of biochemical processes in the organism at the molecular level.
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Prerequisites
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unspecified
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Assessment methods and criteria
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unspecified
Active participation in practical lecturers, written test.
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Recommended literature
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DEVLIN, Thomas M. (2011). Textbook of biochemistry: with clinical correlations. Hoboken: John Wiley.
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Ferrier, D.S. (2018). Biochemistry. Lippincott Illustrated Reviews. Walters Kluwer.
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VOET, D., VOET, G. J., PRATT, W. Ch. Fundamentals of biochemistry: life at the molecular level.
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