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Lecturer(s)
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Berka Karel, doc. RNDr. Ph.D.
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Panáček Aleš, doc. RNDr. Ph.D.
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Hochvaldová Lucie, Mgr. Ph.D.
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Course content
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1. Nanomaterials - basic knowledge from nanomaterial and colloid chemistry, characterization, methods of preparation, properties and application of nanomaterials 2. Toxicology - basic knowledge from toxicology, toxic effect, types of toxic effects, evaluation of toxicity, interaction of toxic substance with biological system 3. Ecotoxicology - basic knowledge from ecotoxicology, evaluation of ecotoxicity 4. Toxicology of nanomaterials - interaction of metal and non-metal nanomaterials with biological systems, gene toxicity, cell toxicity, tissue toxicity, organ toxicity, toxicity to human, biodistribution, tests of nanomaterial's toxicity 5. Ecotoxicology of nanomaterials - nanomaterial source and pollution of individual parts of the environment, admission, distribution and fate of nanomaterials in the environment, ecotoxicity of nanomaterials to aqutic and soil organisms, air pollution by nanomaterials, ecotoxicity tests of nanomaterials 6. Engineered nanomaterials and their toxicity and ecotoxicity
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Learning activities and teaching methods
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Lecture
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Learning outcomes
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The course is aimed on toxicological and ecotoxicological properties of metal and non-metal nanomaterials. The subject will be introduced by lectures covering basic concepts and knowledge of Nanomaterial Chemistry, Toxicology and Ecotoxicology followed by lectures aimed on specific interactions of nanomaterials with biological systems at different levels (cell, tissue, organ etc.) including nanomaterial toxicity to mammalian (human) cells and nanomaterial toxicity to the environment.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam
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Recommended literature
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Everret D. H. (1992). Basic principles of colloid science. RSC, London.
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Komínková, D. (2008). Ekotoxikologie. ČVUT v Praze.
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Kumar, C. ed. (2006). Nanomaterials - Toxicity, Health and Environmental Issues. Weinheim: Wiley-Vch.
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Kvítek, L., Panáček, A. (2007). Základy koloidní chemie. UP Olomouc.
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Monteiro-Riviere, N.A., Lang Tran C. (2007). Nanotoxicology. Informa Healthcare USA.
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Ozin, A.G., Arsenault, A.C. (2005). Nanochemistry - A Chemical Approach to Nanomaterials. Cambridge: RSC Publishing.
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Tichý, M. (2003). Toxikologie pro chemiky. Karolinum UK Praha.
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Walker C.H. (2012). Principles of Ecotoxicology. Routledge.
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