| Course title | Structure and Dynamics of Nucleid Acids |
|---|---|
| Course code | KFC/SDNA |
| Organizational form of instruction | Lecture + Seminar |
| Level of course | Master |
| Year of study | not specified |
| Semester | Summer |
| Number of ECTS credits | 2 |
| Language of instruction | Czech |
| Status of course | Compulsory-optional, Optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
|---|
|
| Course content |
|
Basic types of molecular interactions and forces that create 3D structure of nucleic acids. The mutual effect of these contributions is analysed as well as identified their roles in particular classes of nucleic acids. In direct follow up to other lectures also basic levels also basic levels of description of these interactions from quantum chemistry to empirical potentials with a focus on specific problems associated with studying the fundamental aspects of nucleic acids. The main types of RNA and DNA are discussed with a focus on the principles and their shaping, relation between primary sequence, 3D structure and function, and local or global confirmation variability. The issues are demonstrated on the analysis of the structure and function of ribosomes or other non-cataytic RNA molecules and extraordinary DNA structures such as guanine quadruplexes.
|
| Learning activities and teaching methods |
Monologic Lecture(Interpretation, Training)
|
| Learning outcomes |
|
The subject is aimed on finding the relationship between the primary genetic information and 3D structure of encoded biomolecules is vital for understanding all biochemical processes.
ability to associate information, recognize the structure relations in nucleic acids |
| Prerequisites |
|
unspecified
|
| Assessment methods and criteria |
|
Oral exam
|
| Recommended literature |
|
| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biotechnology and Genetic Engineering (2019) | Category: Chemistry courses | - | Recommended year of study:-, Recommended semester: Summer |
| Faculty: Faculty of Science | Study plan (Version): Bioinformatics (2021) | Category: Informatics courses | - | Recommended year of study:-, Recommended semester: Summer |
| Faculty: Faculty of Science | Study plan (Version): Physical Chemistry (2021) | Category: Chemistry courses | 1 | Recommended year of study:1, Recommended semester: Summer |
| Faculty: Faculty of Science | Study plan (Version): Inorganic and Bioinorganic Chemistry - specialization in Bioinorganic Chemistry (2021) | Category: Chemistry courses | - | Recommended year of study:-, Recommended semester: Summer |