| Course title | Development of Pharmaceuticals |
|---|---|
| Course code | KEB/VYLE |
| Organizational form of instruction | Lecture |
| Level of course | Bachelor |
| Year of study | 3 |
| Semester | Winter |
| Number of ECTS credits | 2 |
| Language of instruction | Czech |
| Status of course | Compulsory-optional, Optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
|---|
|
| Course content |
|
Introduction to drug discovery. Interaction of drugs with molecular targets. Fate of drugs in the body - absorbtion, distribution, excretion. Fate of drugs in the body - metabolism. Prodrugs. Identification and optimization of active compounds. Natural compounds as drugs and inspiration. Biotechnology in drug development and production (antibodies, aptamers, siRNA, CRISPR-Cas, stem cells ...). Farmacogenomics. Clinical trials. Drug approval. Case studies.
|
| Learning activities and teaching methods |
| Lecture |
| Learning outcomes |
|
Introduction to pharmacology and drug development for the biological sciences. Familiarization with the process from the discovery of an active compound to the drug's market launch.
Describe and explain basic principles and strategies of medicinal chemistry. |
| Prerequisites |
|
unspecified
|
| Assessment methods and criteria |
|
Mark
"Presentation of a research paper on drug discovery/pharmacotherapy, followed by a discussion." |
| Recommended literature |
|
| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Experimental Biology - Specialization in Experimental Biology (2021) | Category: Biology courses | 3 | Recommended year of study:3, Recommended semester: Winter |
| Faculty: Faculty of Science | Study plan (Version): Bioanalytical Laboratory Diagnostics in Healthcare - Experimental Biology (2023) | Category: Biology courses | - | Recommended year of study:-, Recommended semester: Winter |