Course: Information Resources in Life Sciences

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Course title Information Resources in Life Sciences
Course code KEB/IZVBM
Organizational form of instruction Lecture + Seminar
Level of course Bachelor
Year of study 3
Semester Winter
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Bělíček Jakub, Mgr.
  • Hájek Libor, Ing.
  • Kryštof Vladimír, prof. RNDr. Ph.D.
Course content
Scientific literature. General bibliographic databases (Pubmed, Web of Science, EBSCO, ProQuest, etc.). Full-text databases, general and publisher. Biotechnological and biomedical databases (NCBI, ExPASy, EMBL-EBI, HGNC). Sequence and structure databases. Comparison of nucleic acids and protein sequences. Searching for genes. Functional genomics. Classification of proteins and proteomics. Posttranslational modifications of proteins. Phylogenetic studies and comparative genomics.

Learning activities and teaching methods
Lecture, Work with Text (with Book, Textbook), Demonstration, Laboratory Work
Learning outcomes
The aim of the course is to teach students how to effectively search, evaluate, and use information resources in biology and medicine, including databases of scientific literature, patents, chemical compounds, and bioinformatics resources.
The student can effectively search for scientific articles in databases (PubMed, Web of Science, Scopus), is familiar with patent databases (Espacenet, WIPO, USPTO), knows how to search for information on chemical compounds (Reaxys, PubChem, ChEMBL), is able to use bioinformatics databases (PDB, UniProt, Ensembl) for individual work, can perform basic gene sequence analyses (alignment, phylogenetic tree construction), is able to design PCR primers and carry out the theoretical preparation of DNA cloning,can cite and correctly handle scientific literature.
Prerequisites
Basic knowledge of biology and chemistry at the bachelor's level. Basic computer and internet skills.

Assessment methods and criteria
Written exam, Seminar Work

Full participation at the seminars is required, 80% successfull passing the test
Recommended literature
  • Baxevanis AD, Ouellette BFF. (2004). Bioinformatics: A Practical Guide to the Analysis of Genes and Proteins. WileyBlackwell; 3rd Edition edition.
  • Bishop, M.J. (1999). Genetics Databases. Academic Press.
  • Claverie, J.M. (2006). Bioinformatics for Dummies. John Wiley & Sons; 2nd Edition edition.
  • Sadek, H.A. (2006). Bioinformatics: Principles and Basic Internet Applications. Trafford Publishing.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Experimental Biology - Specialization in Experimental Biology (2021) Category: Biology courses 3 Recommended year of study:3, Recommended semester: Winter
Faculty: Faculty of Science Study plan (Version): Experimental Biology - Specialization in Experimental Biology of Plants (2021) Category: Biology courses 3 Recommended year of study:3, Recommended semester: Winter