|
Lecturer(s)
|
-
Simerský Radim, Mgr. Ph.D.
|
|
Course content
|
Lecture topics:<br> 1. Membrane and cytoskeletal oragnization of the cell. Cell compartmentation. Molecular structure of biomembranes - composition and function.<br> 2. Membrane traffic pathways - simple and facilitated diffusion, passive and active transport.<br> 3. Ion chanels. <br> 4. Ion channels and signalization in cells of nervous system.<br> 5. Vesicular transport. Endocytosis and exocytosis, fagocytosis.<br> 6. Cell to cell communication. <br> 7. G-proteins, receptors with enzymatic activity.<br> 8. Membrane a nuclear receptors.<br> 9. Transfer of the information to the nucleus (kinase system). Mitogen activated kinases, signaling cascade. <br> 10. Interaction among signaling pathways. Comparisson of analogous signaling pathways of plants and animals.<br> 11. Methods of the study of transport systems.<br>
|
|
Learning activities and teaching methods
|
|
Lecture
|
|
Learning outcomes
|
Interaction among signaling pathways. Comparisson of analogous signaling pathways of plants and animals. Methods of the study of transport systems.
Student should be able to (after attending the course): - describe the membrane and cytoskeletal oragnization of the cell, cell compartmentation and molecular composition and function of biomembranes; - explain the concept of membrane traffic pathways, ion chanels, and vesicular transport; - explain the mechanisms of cell to cell communication, membrane and nuclear receptors and interaction among signaling pathways; - compare the analogous signaling pathways of plant and animals; - describe the methods for study of signaling pathways - design experiments concerning signalling pathways within the cells; - write reports about the experiments and to discuss the results; - evaluate critically research papers.
|
|
Prerequisites
|
unspecified
|
|
Assessment methods and criteria
|
Oral exam
attendance, presentation of scientific paper on given topic, successful passing the oral colloquium
|
|
Recommended literature
|
-
Alberts, B., Bray, D., Johnson, A., Lewis, J., Raff, M., Roberts, K., Walter, P. (2000). Základy buněčné biologie. Espero Publishing, Ústi nad Labem.
|