| Course title | Fundamentals of Genetics |
|---|---|
| Course code | KBC/ZAGE |
| Organizational form of instruction | Lecture |
| Level of course | Master |
| Year of study | 2 |
| Semester | Winter |
| Number of ECTS credits | 2 |
| Language of instruction | Czech |
| Status of course | Compulsory |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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1. History of genetics, basic genetic terms, Mendelian inheritance, Mendel's laws, monohybridism, dihybridism 2. Gene interactions (Intraallelic interactions; Interallelic interactions; epistasis (dominant, recessive), inhibition, complementarity, compensation; cumulative interactions with and without dominance, non-cumulative interactions; evaluation of quantitative traits) 3. Chromosomes (morphology, karyotyping, structure and evolution of chromosomes, methods used for studying chromosomes) 4. Cell divisions (cell cycle, its regulation, mitosis) 5. Cell divisions (meiosis) 6. Genetic linkage (Genetic mapping, linkage maps, factors affecting genetic mapping) 7. Molecular principles of inheritance (structure and function of DNA and RNA, DNA replication) 8. Gene expression (transcription and translation, regulation of gene expression) 9. Sex determination (sex chromosomes, Drosophila, Abraxas and Habrobracon types, other factors affecting sex determination) 10. Mutations (spontaneous a induced mutations, point, chromosomal and genome mutations, reparation processes, significance of mutations during evolution) 11. Extranuclear inheritance (mitochondrial, plastid and cytoplasmic inheritance, plasmids, epigenetics) 12. Population genetics (Hardy-Weinberg principle, outbreeding, inbreeding, effects influencing H-W equilibrium)
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| Learning activities and teaching methods |
Monologic Lecture(Interpretation, Training)
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| Learning outcomes |
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The course is designed for students of the newly accredited field - Bioinformatics. In an adequate and concise form, students will learn about basic principles of inheritance of traits shown on different levels (macromolecules as DNA and RNA, chromosomes, genomes, genes-traits).
Students become competent in genetics and will get acquainted with basic principles of inheritance of traits and its regulation. |
| Prerequisites |
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Successful passing of the subjects from the first four semesters of the study plan Bioinformatics (bachelor level), namely the subjects LRR/OBBC and KBB/AGK.
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| Assessment methods and criteria |
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Oral exam
Successful passing of oral examination. |
| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester | |
|---|---|---|---|---|
| Faculty: Faculty of Science | Study plan (Version): Biophysics (2022) | Category: Physics courses | 2 | Recommended year of study:2, Recommended semester: Winter |