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Lecturer(s)
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Koudeláková Vladimíra, Mgr. Ph.D.
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Course content
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1. Molecular features of solid tumors; 2. Predictive, prognostic, and diagnostic markers in solid tumors; 3. Diagnostic methods based on biochemical, immunohistochemical and cytogenetic methods; 4. Diagnostic methods based on PCR and NGS; 5. Possibilities of markers detection in liquid biopsies; 6. Excursion on the Institute of Molecular and Translational Medicine, the Faculty of Medicine and Dentistry, Palacký University and University Hospital in Olomouc.
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Learning activities and teaching methods
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Lecture
- Attendace
- 13 hours per semester
- Preparation for the Exam
- 20 hours per semester
- Homework for Teaching
- 20 hours per semester
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Learning outcomes
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Students will get acquainted with biochemical, molecular biological, and genetic methods currently used in solid cancer diagnostics. In the beginning, we will discuss individual types of solid tumors and the possibilities of their diagnostics and treatment. We will discuss each tumor marker type with the focus on the possibilities of their detection and their significance for determining the prognosis of the disease or predicting the effectiveness of therapy. Students will get acquainted in detail with the possibilities of current personalized medicine. The lectures will be supplemented by case studies. The course will be completed by an excursion to the Laboratory of Experimental Medicine, the Institute of Molecular and Translational Medicine, the Medical Faculty of Palacky University, and the University Hospital in Olomouc.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Written exam
Written test Colloquium
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Recommended literature
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(2019). Handbook of Biomarkers and Precision Medicine. 1.vyd.. Boca Raton: CRC Press.
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(2022). Laboratory Techniques in cellular and molecular medicine. 1.vyd. Palacky University Press.
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