Course: Structure and Function of Biomacromolecules

« Back
Course title Structure and Function of Biomacromolecules
Course code KBC/BPOL
Organizational form of instruction Lecture
Level of course Bachelor
Year of study 3
Semester Summer
Number of ECTS credits 3
Language of instruction Czech
Status of course Compulsory-optional, Optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Dostálková Silvie, Mgr. Ph.D.
  • Petřivalský Marek, prof. Mgr. Dr.
  • Škrabišová Mária, Mgr. Ph.D.
Course content
Protein structure. Post-translational modification, folding and translocation of proteins. Methods of determining and predicting the structure of proteins. Enzymes and molecular motors. The structure of nucleic acids. Interaction of DNA/RNA and proteins. Polysaccharides, glycoproteins and proteoglycans. Lipids and biological membranes. Membrane proteins. Proteins and protein complexes in intercellular and intracellular signaling

Learning activities and teaching methods
Lecture
  • Preparation for the Exam - 55 hours per semester
  • Attendace - 26 hours per semester
Learning outcomes
Expansion of basic knowledge about the structures and functions of biological macromolecules - proteins, nucleic acids and lipids.
Understanding of the basic principles of formation and modification of the structure of macromolecules, relationships between structure and biological activity, ability to discuss structural parameters of proteins and nucleic acids.
Prerequisites
The course is intended for bachelor students of biochemistry and other students in chemical and biological fields. The recommended prerequisite is completion of the course Fundamentals of Biochemistry (KBC/BCH).

Assessment methods and criteria
Mark, Written exam

The subject ends with an exam in the form of a written test. The test contains 20 questions, each of which is evaluated with a maximum of 2 points for the correct answer and its justification. Test grading scale: F: 0-19, E: 20-23, D: 24-28, C: 29-32, B: 33-36, A: 37-40.
Recommended literature
  • Alberts B, Johnson A, Lewis J, Morgan D, Raff M, Roberts K, Walter P. (2017). Molecular Biology of the Cell, 6th edition. Garland Science.
  • Berg J, Gatto G, Hines J, Tymoczko JL, Stryer L. (2023). Biochemistry, Tenth edition.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Bioinformatics (2021) Category: Informatics courses 2 Recommended year of study:2, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Inorganic and Bioinorganic Chemistry - specialization in Inorganic Materials (2021) Category: Chemistry courses - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Analytical Chemistry (2021) Category: Chemistry courses - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Nanomaterial Chemistry (2024) Category: Chemistry courses 3 Recommended year of study:3, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Biotechnology and Genetic Engineering (2022) Category: Chemistry courses 2 Recommended year of study:2, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Molecular and Cell Biology (2021) Category: Biology courses - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Physical Chemistry (2021) Category: Chemistry courses 1 Recommended year of study:1, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Biochemistry (2022) Category: Chemistry courses 2 Recommended year of study:2, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Bioinorganic Chemistry (2021) Category: Chemistry courses - Recommended year of study:-, Recommended semester: Summer
Faculty: Faculty of Science Study plan (Version): Applied Chemistry (2022) Category: Chemistry courses 2 Recommended year of study:2, Recommended semester: Summer