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Lecturer(s)
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Petřivalský Marek, prof. Mgr. Dr.
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Course content
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Practicing basic information from the KBC/BCH lecture (Fundamentals of Biochemistry) focusing on the connections between the regulatory mechanisms of individual metabolic pathways. Amino acids - chemical formulas, essential AK, dependence of charge on pH, titration curve, isoelectric point. Proteins: peptide bond, structure. Lipids: nomenclature of fatty acids, properties of phospholipids, phospholipases. Enzymes: enzyme activity, Michaelis-Menten equation, substrates and enzyme inhibitors. Carbohydrate metabolism: glycolysis, gluconeogenesis, glycogen, pentose phosphate pathway. Citrate cycle, respiratory chain and ATP synthesis. Regulatory mechanisms and interconnection of metabolic pathways.
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Learning activities and teaching methods
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Lecture, Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook), Group work
- Preparation for the Course Credit
- 26 hours per semester
- Attendace
- 13 hours per semester
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Learning outcomes
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Deepening and practice of the basic knowledge acquired within the framework of the parallel lecture KBC/BCH (Fundamentals of Biochemistry) with an emphasis on the interconnectedness of metabolic reactions and their regulation.
Obtaining and practicing basic information from static biochemistry (amino acids, lipids, sugars, proteins) and the ability to define the main metabolic pathways, their importance, mutual connection and understanding of the principles of metabolic regulation. ?
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Prerequisites
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Basic knowledge of organic chemistry.
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Assessment methods and criteria
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Written exam
Regular participation in classes, successful completion of the final written test with at least 50% of the maximum number of points.
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Recommended literature
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Berg J, Gatto G, Hines J, Tymoczko JL, Stryer L. (2023). Biochemistry, Tenth edition.
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Kodíček M., Valentová O., Hynek R. (2016). Biochemie chemický pohled na biologický svět. Design and Prepress, Praha.
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Koolman J., Rohm KH.:. (2012). Barevný atlas biochemie, 4.vydání. Grada 2012.
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Voet D., Voet, Judith G., Pratt, Charlotte W. (2006). Fundamentals of Biochemistry. New York.
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