|
Lecturer(s)
|
-
Šafářová Dana, Mgr. Ph.D.
-
Nádvorník Petr, RNDr. Ph.D.
|
|
Course content
|
History, important discoveries of Genetics. J.G.Mendel and basic rules of inheritance of genetic information, Mendelian Genetics. Gene interactions, Inheritance of qualitative and quantitative traits. Cell division and the cell basis of reproduction, importance of of mitosis and meiosis. Sex determination, chromosomal and gene primciples of sex determination, the main types. T.H. Morgan and the principle of gene lineage, chromosome mapping. Molecular structure of gene. Central dogma, expresion and multiplication of genetic information, regulation of gene expresion. Principles of Population genetics, Hardy-Weinberg balance, and the main factors influencing it, selection and its importance in speciation. Genetic engineering and the methods and techniques used in molecular genetics (study of gene and gene products, study of evolution). Basics of human genetics, heredity of selected traits in human.
|
|
Learning activities and teaching methods
|
|
Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming)
|
|
Learning outcomes
|
Principles of genetics: mendelism, gene interactions, cell division and reproduction, sex determination, basics of gene and gene expression, mutaions, human genetics, genetics of populations.
Student is able to (after attending the course): - Explain the principles of Mendelian genetics. - Explain the principles of non-Mendelian Genetics: gene interactions, sex and determination of sex, extracellular inheritance. - Define the chromosomal background of inheritance, mitosis and meiosis, gene linkage and its application in construction the genetic maps of chromosomes. - Characterise main molecular mechanism of genetic information transfer, gene structure, replication, transcription and translation, their regulation and genetic manipulations in vitro. - Recall elementary principles of population genetics, Hardy-Weinberg principles, Evolutionary aspects of population variation and speciation. - Explain the inheritance of human characters, and the major methods used in their research. - Describe the elementary rules of inheritance, explain the basic aspects of heredity at the genetic and molecular level according to genetic terminology.
|
|
Prerequisites
|
unspecified
|
|
Assessment methods and criteria
|
Written exam
written test, in extent of the lectures, min 60%
|
|
Recommended literature
|
-
Snustad D.P., Simmons M.J. (2009). Genetika. Brno.
-
Šafářová D. (2011). Kapitoly z obecné genetiky. Olomouc.
|