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Lecturer(s)
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Zůvalová Iveta, Mgr. Ph.D.
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Šafářová Dana, Mgr. Ph.D.
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Course content
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Methods used for specific and non-specific staining of chromosomes. Mitosis in root apexes of onion. Meiosis in anthers of chive. Polytene chromosomes in salivary glands of drosophila. Mendelian inheritance. Sex chromatin, X and Y chromosomes, Q-banding. Inheritance of blood groups, AB0 and Rh system. Drosophila melanogaster, model, inheritance somatic and gonosomal characters, non-mendelian inheritance. Human genetics, pedigree analysis, karyotype. Cloning, man and ethic controversy.
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Learning activities and teaching methods
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Dialogic Lecture (Discussion, Dialog, Brainstorming), Laboratory Work
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Learning outcomes
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Practical introduction into different types of chromosomes, their behaving during cell cycle and mitotic and allotypic division, mendelism and methods of human genetics.
Student is able to (after attending the course): - Prepare basic microscopic cytogenetic slides of tissues and cells stained by specific and non-specific DNA stains. - Characterise the structure of chromosomes, their behaviour during the cell cycle. - Explain principles of mitotic and meiotic division and their significance in GI transfer. - Apply basic laboratory techniques in sex determination in humans. - Evaluate the basic genealogical pedigrees. - Perform simple manipulations with elementary genetic model Drosophila melanogaster.
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Prerequisites
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unspecified
KBB/BZP
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Assessment methods and criteria
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Student performance, Didactic Test
attendance, protocols´ elaboration, 70% test
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Recommended literature
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Snustad D.P., Simmons M.J. (2009). Genetika. Brno.
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Šafářová D. (2011). Kapitoly z obecné genetiky. Olomouc.
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Šafářová D., Uvírová L., Válová P. Cvičení z obecné genetiky. Olomouc.
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