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Lecturer(s)
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Hradil Pavel, prof. Ing. CSc.
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Course content
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The most important group of drugs will be discussed - CNS drugs (antipsychotics, antidepressants, analgesics, hypnotics, anti-allergics and other substances of this group) - Agents acting on the autonomic nervous system - Agents acting on the cholinergic system - Agents acting on the circulatory system and blood - Drugs acting on the urinary and digestive system - Anti-infective agents - Antitumor chemotherapeutics Besides the mentioned drug as well as other biologically active substances both natural and synthetic will be discussed
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Learning activities and teaching methods
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Dialogic Lecture (Discussion, Dialog, Brainstorming), Work with Text (with Book, Textbook)
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Learning outcomes
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Knowledge acquired in the master study about the synthesis and reactivity of key heterocyclic compounds both aromatic and non-aromatic character will be broaden. In practical cases, the biological activity of various heterocyclic molecules will be shown.
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Prerequisites
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unspecified
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Assessment methods and criteria
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Oral exam
Pass the exam.
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Recommended literature
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Eicher T., Hauptmann S. (2003). The Chemistry of Heterocycles. New York, Wiley - VCH.
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Hampl F., Rádl S., Paleček J. (2007). Farmakochemie. VŠCHT Praha.
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Katritzky A. R., Pozharskii A. F. (2000). Handbook Heterocyclic Chemistry. Pergamon, Amsterdam.
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Lüllmann H, Mohr K., Wehling M. (2002). Farmakologie a toxikologie. Grada Praha.
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Patrick G. L. (2005). An Introduction to Medicinal Chemistry. Oxford.
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Smith H.J. (2005). Introduction to the principles of drug design and action. London.
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