Course: Chemistry of Heterocyclic Compounds

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Course title Chemistry of Heterocyclic Compounds
Course code OCH/CHHC
Organizational form of instruction Lecture
Level of course unspecified
Year of study not specified
Semester Winter and summer
Number of ECTS credits 3
Language of instruction English
Status of course unspecified
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Soural Miroslav, doc. RNDr. Ph.D.
Course content
Classification of heterocyclic compounds and general approaches for their naming (trivial vs. systematic nomenclature) Three-membered heterocycles: oxirane, thiirane, azirine, aziridine and others. Four-membered heterocycles: oxethane, thiethane, azet, azetidine and others. Four-membered heterocycles with one heteroatom: furane, benzofurane, tetrahydrofurane, thiophene, benzothiophene, pyrrole, indole, isoindole, karbazole, pyrrolidine and others. Four-membered heterocycles with two heteroatoms: oxazole, benzoxazole, isoxazole, thiazole, benzothiazole, isothiazole, imidazole, benzimidazole, imidazolidine, pyrazole, indazole and others. Four-membered heterocycles with three and four heteroatoms: oxadiazoles, thiadiazoles, triazoles, benzotriazoles, tetrazoles. Six-membered heterocycles with one heteroatom: (benzo)pyrrylium, pyran(one), tetrahydropyrane, chromene, chromane, kumarine, pyridine, pyridones, quinoline, isoquinoline, dibenzopyridine, piperidine and others. Six-membered heterocycles with two or more heteroatoms: dioxanes, oxazines, morpholine, pyridazine, pyrimidine, purine, pyrazine, piperazine, pteridine, benzodiazines, triazines, tetrazines. Seven- and more- membered heterocycles: oxepine, thiepine, azepine, diazepines, azocine, tetrahydropyrroles.

Learning activities and teaching methods
Lecture
Learning outcomes
Specialized course focused on the preparation and reactivity of various heterocyclic compounds
Knowledge in the field of sorting compounds with different heterocyclic scaffolds, representative methods of their synthesis, classification of their reactivity.
Prerequisites
unspecified

Assessment methods and criteria
Oral exam

Basic knowledge in organic chemistry/organic synthesis.
Recommended literature
  • A.R. Katrizky, A.F. Pozharskii. (2000). Handbook of Heterocyclic Chemistry. Pergamon Press, Oxford.
  • Theophil Eicher, Siegfried Hauptmann. (2003). Chemistry of heterocycles. Wiley.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester