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Lecturer(s)
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Dědková Kateřina, Mgr.
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Kukutschová Jana, doc. Mgr. Ph.D.
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Kukutschová Jana, doc. Mgr. Ph.D.
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Course content
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- Introduction, fundamentals of nanotechnology. - Types of exposure, toxicokinetics, examples of biotransformation. - Types of nanomaterials, toxicologically important parameters of nanomaterials. - Toxicity tests (in vitro, in vivo). - Examples of toxic effect of selected nanomaterials (oxidative stress, mutagenita, etc.).
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Learning activities and teaching methods
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Monologic Lecture(Interpretation, Training)
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Learning outcomes
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The students will be introduced to the field of toxicology including interactions of nanomaterials with living systems at the molecular, cell, and organ level. The attention will be devoted to in vitro and in vivo methods used for testing toxicity of nanomaterials. The lecture extends the topics covered in the lectures Risks of Nanotechnologies and deepens the knowledge on environmental and health risks of nanomaterials.
Knowledge Define the main ideas and conceptions of the subject, describe the main approaches of the studied topics, recall the theoretical knowledge for solution of model problems.
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Prerequisites
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unspecified
KEF/NBZN
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Assessment methods and criteria
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Mark
Passing the examination Class attendance
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Recommended literature
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Donaldson K., Borm P. (2007). Particle Toxicology.. CRC Press.
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Klaassen C.D. (2018). Cassaret and Doul's Toxicology. McGraw-Hill Professional.
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Zhao Y. (2006). Nanotoxicology - Interactions of Nanomaterials with Biological Systems.. American Scientific Publishers.
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