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Lecturer(s)
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Luhová Lenka, doc. RNDr. Ph.D.
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Course content
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Regulation at the level of the cell and intercellular communication. Types of signaling molecules and intercellular signaling in eukaryotes. Hormone metabolism. Signal transduction mechanisms mediated by surface receptors. Regulatory mechanisms involved in the control of metabolic pathways. Regulation of carbohydrate, lipid and protein metabolism. Regulation of metabolic pathways during nutrient intake, short-term and long-term starvation. Convergence, divergence and crosstalk of different signaling pathways. Pathological state of the organism - regulation of metabolic events.
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Learning activities and teaching methods
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Lecture
- Attendace
- 26 hours per semester
- Preparation for the Exam
- 55 hours per semester
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Learning outcomes
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Generalization of metabolic pathways, regulation of metabolism, transport systems of cells, signaling pathways.
Define the main terms, describe the basic regulatory, signaling and transport pathways in a living organism.
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Prerequisites
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In the course of the studies so far, basic information from biochemistry has been acquired.
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Assessment methods and criteria
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Written exam
Written exam, 1 hour, 8 tasks; 24 points A 24-22 B 21-18 C 17-16 D 15-14 E 13-12 F less than 12
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Recommended literature
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Berg, J.M., Tymoczko, J.L. and Stryer, L. (2007). Biochemistry. New York, USA.
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Kodíček M, Valentová O, Hynek R. (2022). Biochemie: chemický pohled na biologický svět. VŠCHT Praha.
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Koolman, J., Röhm, K. H. (2012). Barevný atlas biochemie. Praha: Grada.
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Voet D., Voet J. G., Pratt, Ch. W. (2006). Fundamentals of Biochemistry. New York, USA.
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