Course: Molecular Pharmacology

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Course title Molecular Pharmacology
Course code KBB/MOLFA
Organizational form of instruction Lecture
Level of course Master
Year of study not specified
Semester Summer
Number of ECTS credits 2
Language of instruction Czech
Status of course Compulsory-optional
Form of instruction Face-to-face
Work placements This is not an internship
Recommended optional programme components None
Lecturer(s)
  • Zemánková Lenka, PharmDr. Ph.D.
  • Dvořák Zdeněk, prof. RNDr. DrSc.
  • Zůvalová Iveta, Mgr. Ph.D.
Course content
Introduction to pharmacology. Structural factors and physicochemical properties in relation to biological activity. Pharmacokinetics, absorption, distribution, metabolism and excretion of drugs, influencing factors, physiological barriers of distribution, basic pharmacokinetic parameters. Pharmacodynamics, mechanisms of drugs action, drugs interactions, adverse and toxic effects of drugs, preclinical and clinical testing of drugs. The main molecular aspects of selected pharmacotherapeutic groups. Bacterial antibiotic resistance development. Immunotherapy, gene therapy.

Learning activities and teaching methods
unspecified
Learning outcomes
The goal is to give an overview about the interaction of a drug with living organism; and the mechanisms of drug action and their experimental and clinical application.
After the course, the student will be able to discuss basic mechanisms of drugs action. Student is able (after attending of course) to understand and describe: - the theoretical principles of drug action at the molecular level - the molecular aspects of pharmacokinetics and pharmacodynamics - the main molecular targets of selected pharmacotherapeutic groups
Prerequisites
unspecified

Assessment methods and criteria
unspecified
70% test in extent of lecture
Recommended literature
  • Fusek, M., Vítek, L., Blahoš, J., Hajdúch, M., & Ruml, T. (2012). Biologická léčiva: teoretické základy a klinická praxe. Praha: Grada.
  • Katzung, B. G., Masters, S. B., & Trevor, A. J. (2012). Basic & clinical pharmacology. New York, N.Y: McGraw-Hill.
  • Lincová, D., & Farghali, H. (2007). Základní a aplikovaná farmakologie. Praha: Galén.
  • Lüllmann, H., Mohr, K., Hein, L., Wirth, J., & Wenke, M. (2012). Barevný atlas farmakologie. Praha: Grada.


Study plans that include the course
Faculty Study plan (Version) Category of Branch/Specialization Recommended year of study Recommended semester
Faculty: Faculty of Science Study plan (Version): Molecular and Cell Biology (2021) Category: Biology courses 1 Recommended year of study:1, Recommended semester: Summer