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Lecturer(s)
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Dilenko Hanna, Mgr.
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Kolářová Hana, prof. RNDr. CSc.
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Bajgar Robert, MUDr. Mgr. Ph.D.
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Bartoň Tománková Kateřina, doc. Ing. Ph.D.
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Vachutka Jaromír, Mgr. Ph.D.
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Kolaříková Markéta, Mgr.
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Hošíková Barbora, Mgr. PhD.
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Course content
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Introduction to medical biophysics. Fundamentals of measurement. Essentials of informatics, medical informatics. Computer hardware. Computer software. Intermolecular forces. Biophysical properties of liquids and gasses. Molecular structure of living systems. Cell biophysics I. Active and passive transport of molecules. Filtration. Diffusion. Osmosis. Cell biophysics II. Membrane potential. Oxidative hosphorylation. Cell signaling. Fluid balance and electrolyte distribution in human body. Biophysics of blood circulation. Energy exchange between organism and the external environment. Production and transfer of heat. The regulation of body temperature. Electromagnetic spectrum. Introduction to atomic and nuclear physics. Radioactivity. Interaction of ionizing radiation withmatter. Ionizing radiation in medicine. Imaging methods using ionizing radiation. Radiation illness. Essentials of biomechanics. Microscopic methods. Lasers and optical instruments in medicine.
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Learning activities and teaching methods
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Lecture, Monologic Lecture(Interpretation, Training), Dialogic Lecture (Discussion, Dialog, Brainstorming), Laboratory Work
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Learning outcomes
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The main objective is to teach the basic knowledge and skills on the atomic and nuclear physics, thermodynamics, gases and liquid kinetics, molecular constitution of living systems, cells biophysics including biopotencial generation and mechanism of cells excitation, heart function and circulation system biophysics. They obtain skills required for work with technical equipments for biomedical measurement and some diagnostics equipments like ECG recorder and ultrasonograph. The students are also introduced to selected software used in information mining and health care.
The students will be skilled in medical biophysics to be prepared for further study of consequent topics like physiology, pathophysiology, radiology, nuclear medicine etc. Their knowledge on informational technologies support them in effective use of software supporting their study.
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Prerequisites
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Students ought to have fundamental biology and physics attainments at the secondary education level.
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Assessment methods and criteria
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Student performance
100% attendance, measurement protocols completed
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Recommended literature
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Davidovits, P. (2013). Physics in Biology and Medicine. Academic Press.
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Grosman, Z. (1994). Lectures on Medical Biophysics. Olomouc.
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Herman, I.P. (2015). Physics of the Human Body. Springer.
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Hobbie, R. K., & Roth, B. J. (2007). Intermediate physics for medicine and biology. New York: Springer.
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Hrazdira, I. et al. (2012). Fundamentals of biophysics and medical technology. Brno: Masaryk University.
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Hrazdira, I., Mornstein, V., Bourek, A., Škorpíková, J., & Mornstein, V. (2007). Fundamentals of biophysics and medical technology. Brno: Masarykova univerzita.
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Kukurova, E. and coworkers. (1991). Biophysical Elixir for students and absolvents of medicine. Edition of study literature, Bratislava.
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Ronto, G., Tarjan, I., Berkes, L., Gyorgyi, S. (1999). An Introduction to Biophysics with Medical Orientation. Akademiai Kiado.
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Wood, A.W. (2012). Physiology, Biophysics and Biomedical Engineering. CRC Press.
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