| Course title | Physical Chemistry Aimed on the Reactivity of Molecules |
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| Course code | KFC/PGSRM |
| Organizational form of instruction | Lecture |
| Level of course | Doctoral |
| Year of study | not specified |
| Semester | Winter and summer |
| Number of ECTS credits | 20 |
| Language of instruction | Czech, English |
| Status of course | Compulsory-optional |
| Form of instruction | Face-to-face |
| Work placements | This is not an internship |
| Recommended optional programme components | None |
| Lecturer(s) |
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| Course content |
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The importance of kinetics and mechanisms of chemical reactions. Study of equilibrium processes. Acid - basic equilibrium. Generalized Acid function. Study of chemical reactions. Inner and outer factors influencing reactivity. Basic and advanced kinetic equations. Physical and chemical methods of reaction rate determination. Experiment evaluation. Thermodynamics of chemical reactions. Principle of similarity and its application. Salt effects. Bodenstein approximation of quasi-stationar state. Consequent reaction. Superposed equilibrium. Determination of activation parameters of chemical reaction. Classification of solvents and their influential character on the chemical reactivity. Empiric and semi-empiric parameters of solvent polarity. Solvent effects of mixed solvents. Nucleofility and its quantitative description. Isotopic effects. Substitution effects. Bronsted relation. Substitution effects and Hammett equation. Quantitative description of substitution effects based on the effect separation. Application of physical methods in the study of relations between structure and characteristics of organic substances. Application of physical methods in the course of mechanism study of organic reactions. The relationship between the structure of the organic substances and their biological efficiency.
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| Learning activities and teaching methods |
Dialogic Lecture (Discussion, Dialog, Brainstorming)
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| Learning outcomes |
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The lectures are focused on advanced physical chemistry specialized on reactivity of molecules
ability to integrate knowledge, explain reactivity following physical chemistry |
| Prerequisites |
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unspecified
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| Assessment methods and criteria |
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Oral exam
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| Recommended literature |
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| Study plans that include the course |
| Faculty | Study plan (Version) | Category of Branch/Specialization | Recommended semester |
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