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Lecturer(s)
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Berka Karel, prof. RNDr. Ph.D.
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Vrána Oldřich, doc. RNDr. CSc.
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Course content
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The attention will be paid to the description of behaviour of metal complexes in aqueous media and in the conditions that are adequate to the physiological conditions. There will be also discussed possible interactions of biologically significant biomacromoecule as DNA, RNA and proteins, stability of the formed products and their influence on the functions of the above mentioned biomacromolecules. In the course there will be also discussed suitable methods of study of the interactions between the metal complexes and biological material.
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Learning activities and teaching methods
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Dialogic Lecture (Discussion, Dialog, Brainstorming)
- Preparation for the Exam
- 0 hours per semester
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Learning outcomes
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The course in aimed on the explanation and application of methods that are used in the study of metal complexes with biological material interactions.
ability to integrate knowledge, propose solutions, formulate conclusions important for the utilization of comlex compounds in anti-tumor therapy
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Prerequisites
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unspecified
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Assessment methods and criteria
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Oral exam
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Recommended literature
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Bertini J., Gray H.B., Lippard S.J. (1994). Bioinorganic Chemistry. Mill Valey California.
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Kodíček, M., Karpenko, V. (2000). Biofyzikální chemie. Academia Praha.
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Lippard, S. J., Berg, J. M. (1994). Principles of Bioinorganic Chemistry. University Science Books.
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